Pinghu Zhanpeng Hot Melt Adhesive Web & Film Co., Ltd

Onze diensten

Biocompatible hdpe mesh thermoplastic polyurethane  membranes are promising candidates as a scaffold; however, their lack of a suitable porous structure and antibacterial activity has limited their application. 

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Antibiotics no sew hemming are generally used for preventing bacterial infections, but the global emergence of drug-resistant bacteria continues to cause social concer.Consequently, we prepared a flexible dressing based on a TPU membrane with a specific porous structure and then modified it with a biomimetic polydopamine coating to prepare in situ a nano-silver based composite via a facile and eco-friendly approach.

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SEM elastic medical tape images showed that the  membranes were characterized by an ideal porous structure  that was decorated with nano-silver particles.

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ATR-FITR and XRD spectroscopy fabric medical tape further confirmed the stepwise deposition of polydopamine and nano-silver. Water contact angle measurement indicated improved surface hydrophilicity after coating with polydopamine. Tensile testing demonstrated that the  membranes had an acceptable mechanical strength and excellent flexibility.

Subsequently, bacterial hdpe mesh fabric suspension assay, plate counting methods and Live/Dead staining assays demonstrated that the optimized  membranes possessed excellent antibacterial activity against P. aeruginosa, E. coli, S. aureus and MRSA bacteria, while CCK8 testing, SEM observations and cell apoptosis assays demonstrated that they had no measurable cytotoxicity toward mammalian cells.

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Prive

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ZZP

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MKB

  • Address: No. 2666 Xinkai Road, Economic Development Zone, Pinghu City, Zhejiang Province
  • Phone：+86 573 85092050
  • Fax：+86 573 85032007
  • E-mail：zhanpengweb7@hotmelt-zp.com
  • Web:https://www.hotmelt-zp.com/